Normalised counts of DHS data
De-regulated DNase I Hypersentive sites identified by Assi et al in Nature Genetics 2018
Up regulated DHS files
CEBPA 396_upregulated_DHS
FLT3-ITD_3085_upregulated_DHS
FLT3-ITD/NPM1_2228_upregulated_DHS
inv(16)_5182_upregulated_DHS
NPM1_4088_upregulated_DHS
RUNX1_805_upregulated_DHS
t(8;21)_5366_upregulated_DHS
Down regulated DHS files
CEBPA_6721_downregulated_DHS
FLT3-ITD_3067_downregulated_DHS
FLT3-ITD_NPM1_3677_downregulated_DHS
inv16_6187_downregulated_DHS
NPM1_4916_downregulated_DHS
t8-21_6485_downregulated_DHS
These tables contain DHSs data that can be used as bed files. They show the hg38 chromosomal coordinates of DHSs which are 3 fold up or down regulated in AML mutation-specific groups relative to PBSCs. The DHSs are ranked in decreasing order of the fold difference values shown as log2 values in the right hand column of each table